![]() ![]() An early invasive strategy was shown to be beneficial by the FRISC II, TACTICS-TIMI 18 and RITA-3 studies, especially in the subgroup of patients who were at a high risk, such as those patients presenting with an elevated cardiac troponin level. In five large, randomized trials 18- 22, a routine, early invasive strategy (early angiography followed by revascularization, depending on the angiographic findings) was compared with a "conservative" strategy (angiography and subsequent revascularization only if medical therapy failed or substantial residual ischemia was documented). And the duration of admission to the coronary care unit was significantly longer in group II (3.1 vs. However, for the high risk patients, there was a significantly lower in-hospital mortality in group I (3.3% vs. For the low and moderate and high risk patients, no significant differences of the in-hospital mortality ( p = 0.872, p = 0.052, respectively) were observed between two groups. The patients in both groups were classified into 3 sub-groups according to the TIMI risk score: 742 patients (310 patients of group I and 432 patients of group II) had a TIMI risk score of 0-2 points (the low risk group), 1,556 patients (687 patients of group I and 869 patients of group II) had a TIMI risk score of 3-4 points (the moderate risk group) and 547 patients (237 patients of group I and 310 patients of group II) had a TIMI risk score of 5-7 points (the high risk group). The estimated in-hospital mortality was 2.1% in group I and 4.8% in group II (relative risk: 2.36, 95% confidence interval: 1.51 to 3.71 p < 0.001) ( Table 5). ![]() Korea Acute Myocardial Infarction Registry (KAMIR) Study Group of Korean Circulation Society, Korea. 1Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea.ĢDepartment of Internal Medicine, Kyungpook National University, Daegu, Korea.ģDepartment of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea.ĤDepartment of Internal Medicine, Pusan National University Hospital, Busan, Korea.ĥDepartment of Internal Medicine, Yeungnam University Hospital, Daegu, Korea.ĦDepartment of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea.ħDepartment of Internal Medicine, Chonbuk National University Hospital, Jeonju, Korea.ĨDepartment of Internal Medicine, Jeonju Presbyterian Medical Center, Jeonju, Korea.ĩDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ġ0Department of Internal Medicine, National University, Cheongju, Korea.ġ1Department of Internal Medicine, Konyang University, Daejeon, Korea.ġ2Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea.ġ3Department of Internal Medicine, Kyung Hee University Hospital, Seoul, Korea.ġ4Department of Internal Medicine, Yonsei University Wonju Hospital, Wonju, Korea.ġ5Department of Internal Medicine, Wonju University Hospital, Wonju, Korea.ġ6Department of Internal Medicine, Catholic University Hospital, Seoul, Korea.ġ7Department of Internal Medicine, Asan Medical Center, Seoul, Korea. ![]()
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